There actually was a real Mexican cartel named La Familia - it was the Michoácan cartel that was based in the Mexican state of Michoacán. It was formed around 1980 so it could be used as the basis for the game La Familia cartel. If you read about it they would be a very interesting adversary in the Mexican Civil War as they actually were originally founded to help the poor - i.e. a Robin Hood for the modern times - but one that was incredibly violent.
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