Fallout might be an issue
I calculated fallout based on prevalent wind direction for the nearest 3 weather stations for an average November.
Nearest strikes
2.9 km SxSE of Texas City, TX, 1500 Kt
42.6 km SxSE of Baytown, TX, 2000 Kt
44.6 km SxSE of Deer Park, TX, 1250 Kt
64.1 km SE of Houston, TX, 1500 Kt
86.5 km ExNE of Sweeney, TX, 500 Kt
110.5 km SW of Nederland, TX, 500 Kt
110.6 km WxSW of Port Arthur, TX, 3000 Kt
111.0 km SW of Beaumont, TX, 1500 Kt
144.5 km S of Lamont, TX, 750 Kt
186.3 km WxSW of West Lake, LA, 500 Kt
300.4 km NE of Corpus Christi, TX, 1000 Kt
317.3 km SE of Robinson, TX, 750 Kt
331.3 km E of Randolf AFB, TX, 250 Kt
368.7 km SxSW of Shreveport, LA, 250 Kt
380.1 km WxSW of Baton Rouge, LA, 1500 Kt
399.3 km W of Convent, LA, 750 Kt
420.0 km W of Garyville, LA, 750 Kt
438.7 km W of Norco, LA, 1000 Kt
448.1 km SxSE of Carswell AFB, TX, 500 Kt
477.2 km W of Belle Chase, LA, 750 Kt
482.1 km W of Meraux, LA, 250 Kt
584.0 km SE of Dyess AFB, TX, 500 Kt
621.3 km W of Pascagoula, MS, 1250 Kt
763.1 km S of Tulsa, OK, 500 Kt
814.2 km W of Eglin AFB, FL, 1000 Kt
My games were always about rebuilding so I have some useful tools to find resources in an area
Here are the nearest renewable/Nuclear power sources
77.2 km SE of Sunset Farms - Land Fill Gas - 2219 kWT
130.6 km ExNE of South Texas 2 - # of reactors: 2 - 1280/1280 Mwt
196.9 km WxSW of Agrilectric Power Partners Ltd - Agra Waste - 7884 kWT
237.8 km SxSW of Toledo Bend - 40097 kWT
255.3 km E of Small Hydro Of Texas Inc - 762 kWT
302.6 km ExSE of Austin - 6296 kWT
320.7 km ExSE of Marshall Fd - 19419 kWT
327.3 km W of M A Patout Son Ltd - Agra Waste - 176 kWT
355.6 km E of Falcon Dam - 4154 kWT
362.5 km ExSE of Marble Fls - 3245 kWT
373.0 km ExSE of Granite Sh - 4777 kWT
373.6 km WxSW of River Bend 1 - # of reactors: 1 - 978 Mwt
378.9 km ExSE of Buchanan - 3882 kWT
405.1 km SW of Sidney A Murray Jr Hydroelectric Station - 96124 kWT
428.9 km SxSE of Nolte - 8960 kWT
436.2 km SE of Comanche Peak - # of reactors: 2 - 1084/1124 Mwt
437.4 km W of Waterford 3 - # of reactors: 1 - 1089 Mwt
463.7 km SxSE of DFW Gas Recovery - Land Fill Gas - 4496 kWT
466.5 km SxSE of Lewisville - 1277 kWT
468.9 km SE of H 4/5 - 2876 kWT
479.7 km ExSE of M Sheppard - 1899 kWT
482.5 km SW of Grand Gulf 1 - # of reactors: 1 - 1263 Mwt
506.3 km SxSE of Roberts - 285 kWT
512.7 km SxSW of Crossett Paper - Wood Waste - 190 kWT
523.4 km SxSE of Denison - 40356 kWT
Here are the nearest 25 mines
53.0 km SxSW of Laporte/Deerpark Plants Div Of Texas Brine - Salt
64.4 km E of Chemicals & Metals - Magnesium
64.4 km E of Freeport Plant - Salt
71.8 km SE of Hockley Plant - Salt
71.8 km SE of Swilley Pit & Plant - Industrial Sand And Gravel
71.8 km SE of Pierce Junction Plant - Salt
87.3 km SW of Jefferson Plant - Salt
97.1 km S of Tec Minerals Plant 3 - Industrial Sand And Gravel
101.2 km ExSE of Blue Ridge Plant - Salt
124.7 km ExNE of Clemville Plant - Salt
129.1 km SxSW of Barry & Barry Pit & Plant - Industrial Sand And Gravel
164.5 km E of Eagle Lake Plant - Industrial Sand And Gravel
164.5 km E of Industrial Sand Operations - Industrial Sand And Gravel
175.9 km SW of Industrial Chemical Division - Salt
206.1 km ExSE of Balcones Minerals Corp - Fuller'S Earth
206.1 km ExSE of Flatonia Pits - Bentonite
214.4 km SxSW of Deweyville Dredge - Industrial Sand And Gravel
221.0 km S of Angelina County Pits - Bentonite
238.1 km SW of Kinder Plant - Industrial Sand And Gravel
251.0 km ExSE of Hicks Mine
263.2 km E of Texas Pits - Bentonite
280.8 km S of Troup Operations - Ball Clay
298.3 km W of Avery Island - Salt
298.3 km W of Morton Salt Weeks Island Mine And Plant - Salt
300.8 km ExNE of Corpus Christi - Salt
25 nearest steel plants
121.3 km SW of Multiple
263.2 km SxSE of Nucor Steel Texas
306.4 km E of Structural Metals
406.1 km S of Lone Star Steel
411.6 km SxSE of Chaparral Steel
428.3 km W of Bayou Steel
467.4 km SxSW of Smi Steel Arkansas
559.6 km SW of Multiple
565.3 km SxSE of Mid American Steel & Wire
581.6 km SW of Multiple
671.8 km SxSE of Acker Industries
679.2 km WxSW of Ipsco Steel Alabama
679.4 km S of Quanex Macsteel
771.3 km S of Metal Services
771.8 km S of Sheffield Steel
777.2 km SxSW of Arkansas Steel Associates
791.7 km SW of Birmingham Steel Memphis Steel
816.4 km WxSW of Multiple
870.5 km SxSW of Multiple
876.3 km WxSW of United States Pipe & Foundry
873.0 km SW of Birmingham Steel Ripley Powdered Metal
879.5 km WxSW of Koppers Industries Woodward Coke
884.3 km WxSW of USS Fairfield Works
894.3 km WxSW of Multiple
900.9 km WxSW of Abc Coke Div Of Drummond
Chemical plants
11.6 km SE of Gaf Corporation - Organic Chemicals | Employees 200
12.0 km SxSW of Climax Chemical Company - Muriate Of Potash | Employees 3
15.1 km SE of Gaf Corporation - Industrial Gases | Employees 200
15.6 km SE of Union Carbide Corporation - Industrial Gases | Employees 1400
24.4 km SE of Sea Lion Chemical Inc - Organic Chemicals | Employees 38
36.8 km SxSE of Calgon Corporation Delaware - Medicine/Botanical Chemicals | Employees 38
38.0 km SE of Polycom-Huntsman Inc - Inorganic Chemicals | Employees 200
40.0 km SE of Haldor Topsoe Inc - Catalysts Chemical | Employees 41
40.3 km SxSE of Hoechst Clanese Chemical Group - Organic Chemicals | Employees 35
41.1 km E of Monsanto Company - High Purity Chemicals | Employees 887
42.0 km SxSE of Dixie Chemical Company - Inorganic Chemicals | Employees 200
42.1 km SxSE of Amoco Chemical Company - Medicine/Botanical Chemicals | Employees 45
42.3 km SxSE of Haldor Topsoe Inc - Catalysts Chemical | Employees 43
42.5 km SxSE of Phillips Petroleum Company - Catalysts Chemical | Employees 160
42.8 km SxSE of Bayshore Industrial Inc - Plastics | Employees 50
42.9 km SxSE of Arco Chemical Company - Propylene | Employees 300
43.2 km SxSE of Lonza Inc - Inorganic Metal Compounds | Employees 80
43.3 km SxSE of Hoechst Celanese Corporation - Org A/Cyclic Plasticizers | Employees 250
43.4 km SxSE of Fmc Corporation - Bulk Org Medicinal Chemicals | Employees 58
43.8 km SxSE of Himont Usa Inc - Polypropylene Resins | Employees 155
43.8 km SxSE of Hoechst Clanese Chemical Group - Inorganic Chemicals | Employees 650
44.9 km SxSE of Southern Ionics Inc - Inorganic Chemicals | Employees 30
45.3 km SE of Kaneka Texas Corporation - Plastics Materials | Employees 85
45.3 km SE of Cain Chemical Inc - Ethylene Glycols | Employees 100
45.5 km SxSE of Ppg Industries Inc - Organic Chemicals | Employees 100
Military Bases
47.6 km SxSE of 272 Engineering Installation Squadron (ANG) - Air Force
48.1 km SE of 147 Fighter Wing (ANG) - Air Force
244.7 km SW of ARNG (RC) Major Training Center - Army
249.3 km SW of Training Center - Army
284.1 km NE of Naval Station - Navy
293.1 km ExSE of 10 AF HQ (AFR), 924 Fighter Wing (AFR) - Air Force
300.4 km NE of Flight Training - Navy
336.9 km E of HQ Aetc, Af Prsnl Cntr, Af Rcrtng Serv, 12 Ftw - Air Force
350.6 km SE of 1St Cavalry/4th Inf Div (Mech) - Army
350.7 km E of Medical Training HQ - Army
351.4 km E of Human Systems Center, 70 Air Base Group - Air Force
353.7 km NE of Flight Training - Navy
365.3 km E of San Ant Alc, HQ Air Intel Agncy, 76 Abw, 67 Intel - Air Force
366.3 km E of Reserve Component Training - Army
369.5 km E of 37 Training Wing, 59 Medical Wing - Air Force
372.1 km E of Logistics Depot - Army
374.5 km SxSW of 8 AF HQ, 2 Bw, 917 Wing (AFR) - Air Force
381.7 km S of Ammunition Production - Army
387.4 km SxSW of Ammunition Production - Army
434.6 km SxSE of Reserve Air Training - Navy
445.5 km WxSW of 236 Combat Communications Squadron (ANG) - Air Force
455.7 km SxSE of ARNG (RC) Major Training Center - Army
460.5 km SxSE of 301 Fighter Wing (AFR) - Air Force
461.5 km SxSE of Reserve Air Training - Navy
465.0 km SxSW of 254 Combat Communications Group (ANG) - Air Force
Airfields/Heliports
4.7 km WxSW of UTMB - Airport
4.8 km SW of Shell Pelican Island Heliport - Airport
4.8 km NE of Scholes Field - Airport
4.9 km WxSW of University of Texas Medical Branch Hospital Helipo - Airport
5.1 km SW of Dresser Industries/Magcobar Heliport - Airport
6.6 km NE of Tourist Ride Services Heliport - Airport
9.6 km WxSW of Galvestonian Heliport - Airport
11.2 km SxSW of Houston Oil and Minerals Port Bolivar Heliport - Airport
12.4 km SxSW of Houston Oil and Minerals Port Bolivar Number 2 Hel - Airport
19.6 km SE of Mainland Regional Health Care System Heliport - Airport
19.9 km ExSE of Johnnie Volk Field - Airport
20.6 km ExSE of HHI Hitchcock Heliport - Airport
22.3 km SE of Austinia Airport
25.0 km SE of Laseair Airport
26.0 km E of Old Forker Ultralight Airport
26.1 km SxSE of B and S Ultralight Airport
26.5 km SxSE of Ellis Airport
27.0 km SW of Seafood Warehouse Park Airport
27.0 km SxSW of Houston Oil and Minerals Smith Point Heliport - Airport
27.6 km ExSE of Pee Wees Heliport - Airport
27.8 km ExSE of Rebel Field - Airport
29.1 km E of Creasy Airport
33.0 km SE of Houston Gulf Airport
34.5 km SE of Pier 5 Heliport - Airport
34.7 km ExSE of Golden Pegasus Ranch Heliport - Airport
Hope some of that will be useful.