I keep coming back to the logical consequences of the takedown of PB. If it is via a new bioweapon, where else does this exist and how does it not doom the Project and/or humanity? If it is via something inserted into the PB supply chain, where else was it inserted, what does that mean for the Project, and why does that level of penetration not doom the Project in other ways? If the Russians are involved... oy vey.
I don't like the bioweapon, and I like it even less if it is introduced via contaminated vaccines. Problem 1 is that it requires some significant penetration into Morrow's structure by Krell, and that penetration should have wide-spread consequences throughout the game. Problem 2 is that the large variability in incubation and symptomatic times means that PB should either have overcome the problem or at least taken much better steps to account for their own demise.
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