As well as T2K I also like GURPS - largely for the pleasure in reading such a well thought out logical system (playing RPGs is another matter these days for me) - one of the best settings I've come across is Transhuman Space. I read these books for pleasureas I think some of the ideas contained in them are wonderful.
One book I bought was "Toxic Memes" which is all about just this kind of subject:
http://www.sjgames.com/transhuman/toxicmemes/