As the books are vague on the smaller nukes, if you can justify a particular location as a target, you can nuke it. You can also not nuke an otherwise prime target due to missile failure, changing military priorities or any number of other reasons.
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If it moves, shoot it, if not push it, if it still doesn't move, use explosives.
Nothing happens in isolation - it's called "the butterfly effect"
Mors ante pudorem
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