Breaking it right down, I'd say the Acrobatics skill of 2.1/2.2 is probably the best way to go. Apply negative modifiers for every 5kg block of gear carried, plus other modifiers for the actual action attempted.
Use of some equipment may increase the chance of success such as a pole to assist in a vault, or swinging across a chasm on a rope (rather than a straight jump).
*Acrobatics first appeared in the Twilight Encounters box before 2.2 was released.
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If it moves, shoot it, if not push it, if it still doesn't move, use explosives.
Nothing happens in isolation - it's called "the butterfly effect"
Mors ante pudorem
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