Can't say for sure on meds...... on one hand, the absolute darkness, 55 degree temp (its always 55 below 20 feet), and the nitrogen environment is perfect for storing anything. On the other hand, if it is the chemicals breaking down themselves because they react to one another?
GM, call. However, I would rule these are good. After all the Project buried some of the caches and bolt holes 20 years prior to the event and expected a 3-5 year wait after the war before activating.
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