Doesn't "fatigue" already penalise the character in that manner?
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Originally Posted by BYB 2.2 ed
Effects of Fatigue: All of a character's effective attributes are reduced by 1 for each level of fatigue. If any attribute is reduced to 0, the character becomes unconscious
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Some of the diseases can impose fatigue level 3. This is on top of the usual fatigue a character may have from Hard Work or lack of sleep. It's quite possible for some characters (ANY stat of 4 or less) to find themselves passing out.
Note the other effects of fatigue:
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Originally Posted by BYB 2.2 ed
Direct fire is made more difficult by fatigue. When rolling for a direct fire task, after all adjustments are made for range, recoil, etc., the die roll is increased according to the character's fatigue level. For each level of fatigue, the die roll is increased 3 points at short range, 2 points at medium range, and 1 at long range or longer.
Load is reduced by 10% per level of fatigue.
Throw range is reduced by 10 meters per level of fatigue.
Unarmed combat damage is reduced by one per level of fatigue.
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So not only are they at risk of passing out, they cannot shoot as well, carry as much, or punch as hard. Rolling against skills is also more difficult giving it's against skill plus controlling attribute in most cases.
V1 is very similar with differences being mainly which attributes are effected, the adjustments for a D100 instead of D20 system, etc.