My thoughts on this, first I am a non-drinker/smoker/all the above. So some of this may be skewed by that. But short term I see tobacco, and alcohol being very prized, as a link to the real world. But as time goes on, I would guess that alcohol would be come a mixed bag, by that I mean it would be for medical, and fuel, but less so for recreational. Tobacco the demand for it even more so would drop off. As for drugs (both what today are legal and illegal) again would be a mixed bag. Something that can not be grown, but you need to take every day, would run out quickly, then you have to deal with the fall out of that. For example a former co-worker of mine had a kidney transplant, and was on anti-rejection meds. If he runs out he is dead man walking, has a short time before the damage is to much, and after that even if he gets more it does not matter. Now on the other side my best friend takes multivitamins every day as he does not like to eat a well balanced diet. If he runs out, either he starts eating a well balanced diet, or he will have the issues of what he is not getting (likely having the issues with supply as I understand the game settings). So what I guess I am getting at here is that if you need them they would be worth a lot, but if you do not there value would be low to you (unless you planed to sell them), but as time went on there value would diminish. Illegal drugs (by today's standard) I could see some of them being used for medical purposes, depending on how hard they are to grow where you are, I could also see them being used for recreation. I do not see there being large numbers of "junkies" as they are not normally the most productive member of the community. With the limited supplies most communities have, keeping someone who is not productive (and/or is a liability) is not likely to be many, also with limited supplies why would I spend them on something that is not going to help keep me alive, or improve my health? There will be some, just as there are some that can run a 6 min mile while smoking, but they are going to be the exception I think.
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