Bio weapon attacks against large scale population centers - where you get 33-50% casualties or more - definitely did not happen in the T2K canon - stuff like that would have been mentioned for sure, most likely with the words "nuclear response" right afterward. I agree with Raellus - small scale may have happened - but anything that takes out huge swaths of population is not in the canon at all.
Having that used would move a story or sourcebook from possible canon into more the area covered by Twilight Nightmares and not into something that could be taken as canon.
Plus you go from a war that is horrific but where some kind of civilization survives to more like The Road where basically any kind of civilization would be finished for good - especially when you add in the effects already seen in the canon.
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