Twilight 2000 2.2e vs. 4e Celebrity Deathmatch

[HaplessOperator]

I've been split on 2.2 and 4e for a new game, after discovering the hype around 2.2 and giving the books a look-through, but i'm leaning towards a heavily modified 4e (feel free to sway my mind; it's probably easily done).

For those with experience with both, and having seen several threads running on the topic, I'm keenly interested in knowing what specific or cohesive changes anyone reading would make to either the 4e timeline or mechanics to bring a greater degree of verisimilitude and feel of 2.2 into the 4e setting and mechanics.